---
title: "SEPI1: Disease Process Overview (Georgia Science standard)"
code: SEPI1
cite_as: Georgia Standards of Excellence, Science, SEPI1
subject: science
grades:
  - high-school
language: en
canonical_url: https://georgiahomeroom.org/standards/code/SEPI1
md_url: https://georgiahomeroom.org/standards/code/SEPI1.md
alternate_language_url: https://georgiahomeroom.org/es/standards/code/SEPI1.md
source_url: https://case.georgiastandards.org/ims/case/v1p1/CFDocuments/27a08dc6-416e-11e7-ba71-02bd89fdd987
source_last_changed: 2025-05-29
data_built: 2026-09-18
publisher: Georgia Homeroom, a free public-interest project of Georgia Civic Data. Not affiliated with or endorsed by the Georgia Department of Education or any school district.
up: https://georgiahomeroom.org/standards/science/high-school.md
index: https://georgiahomeroom.org/standards/index.md
---

# SEPI1: Disease Process Overview

Obtain, evaluate, and communicate information to understand and analyze the disease process.

- Subject: Science
- Appears in: High School, https://georgiahomeroom.org/standards/science/high-school.md

## Expectations

- **SEPI1.a**: Obtain, evaluate and communicate information about the history and uses of epidemiology. (Clarification statement: This element is intended to include scientists, public health organizations and scientific breakthroughs.)
- **SEPI1.b**: Ask questions about diseases and pathogens that cause them.
- **SEPI1.c**: Construct an explanation of the body’s defense mechanisms and how illness results when the mechanisms fail to maintain homeostasis.
- **SEPI1.d**: Construct an argument from evidence to explain how the rapid evolution of pathogens results in diseases that will continue to be a public health concern. (Clarification statement: Instruction should include an emphasis on the importance of antibiotic resistance from both domestic and global perspectives).
- **SEPI1.e**: Develop and use models to explain the different modes of disease transmission and how timing of exposure during the disease process affects spread of disease.

## Georgia Milestones coverage

No Georgia Milestones blueprint cites this standard.

Source: Georgia Standards of Excellence, published by the Georgia Department of Education at case.georgiastandards.org.