---
title: "SEPI4: Disease Causation Analysis (Georgia Science standard)"
code: SEPI4
cite_as: Georgia Standards of Excellence, Science, SEPI4
subject: science
grades:
  - high-school
language: en
canonical_url: https://georgiahomeroom.org/standards/code/SEPI4
md_url: https://georgiahomeroom.org/standards/code/SEPI4.md
alternate_language_url: https://georgiahomeroom.org/es/standards/code/SEPI4.md
source_url: https://case.georgiastandards.org/ims/case/v1p1/CFDocuments/27a08dc6-416e-11e7-ba71-02bd89fdd987
source_last_changed: 2025-05-29
data_built: 2026-09-18
publisher: Georgia Homeroom, a free public-interest project of Georgia Civic Data. Not affiliated with or endorsed by the Georgia Department of Education or any school district.
up: https://georgiahomeroom.org/standards/science/high-school.md
index: https://georgiahomeroom.org/standards/index.md
---

# SEPI4: Disease Causation Analysis

Obtain, evaluate, and communicate information to analyze associations and causations of health and disease.

- Subject: Science
- Appears in: High School, https://georgiahomeroom.org/standards/science/high-school.md

## Expectations

- **SEPI4.a**: Use mathematical models to predict and explain the relationship between variables and the presence, nature, and impact of any confounding factors.
- **SEPI4.b**: Analyze and interpret epidemiological data as well as evidence from other scientific disciplines to determine if exposure to a variable causes a disease. (Clarification statement: Students should understand the differences between confounding and associated variables when analyzing data.)

## Georgia Milestones coverage

No Georgia Milestones blueprint cites this standard.

Source: Georgia Standards of Excellence, published by the Georgia Department of Education at case.georgiastandards.org.